Maintenance of this website is ceased as successful operation of the research group "Biomolecular NMR Spectroscopy" closed at end of 2015. This web site will be closed soon.
The structure-function relationship for biomolecules relevant to ageing
processes and age-related disease were recent focus of the Biomolecular
NMR Group in order to understand damaging and repair mechanisms in mechanistic
molecular terms. This research included the cytotoxic oligomeric beta amyloid
peptide involved in the pathogenesis of Alzheimer's Disease, the DNA
repair/replication helicases RecQL4 and MCM, the DNA repair protein Aprataxin
and heme-binding proteins. This work also included methods development for
solid-state and liquid-state NMR spectroscopy as well as for CD spectroscopy.
The results of the former Research Interests are itemized in several publications. Software generated by the former group is still provided by this website.