
Publications (Former Research Group "Biomolecular NMR Spectroscopy")
- 2016
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N. Goradia, A. Wißbrock, C. Wiedemann, F. Bordusa, R. Ramachandran,
D. Imhof, O. Ohlenschläger
"1H, 13C, and 15N resonance assignments for the pro-inflammatory cytokine interleukin-36α"
Biomolecular NMR Assignments (2016, Epub ahead of print)
[DOI: 10.1007/s12104-016-9694-7]
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H. H. Brewitz, N. Goradia, E. Schubert, K. Galler, T. Kühl, B. Syllwasschy,
J. Popp, U. Neugebauer, G. Hageluken, O. Schiemann, O. Ohlenschläger, D. Imhof
"Heme interacts with histidine- and tyrosine-based protein motifs and inhibits
enzymatic activity of chloramphenicol acetyltransferase from Escherichiacoli."
Biochim Biophys Acta 1860 (6) (2016), 1343-1353
[DOI: 10.1016/j.bbagen.2016.03.027]
[Abstract]
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C. Wiedemann, P. Bellstedt, S. Häfner, C. Herbst, F. Bordusa,
M. Görlach, O. Ohlenschläger, R. Ramachandran
"A Set of Efficient nD NMR Protocols for Resonance
Assignments of Intrinsically Disordered Proteins"
ChemPhysChem (2016), (Epub ahead of print)
[DOI: 10.1002/cphc.201600155]
[Abstract]
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S. T. Kumar, J. Leppert, P. Bellstedt, C. Wiedemann, M. Fändrich,
M. Görlach
"Solvent Removal Induces a Reversible β-to-α Switch in Oligomeric
Aβ Peptide"
Journal of Molecular Biology 428 (2A) (2016), 268-273
[DOI: 10.1016/j.jmb.2015.05.002]
[Abstract]
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E. Duchardt-Ferner, S. R. Gottstein-Schmidtke, J.E. Weigand, O. Ohlenschläger,
J.-P. Wurm, C. Hammann, B. Suess, J. Wöhnert
"What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand
Specificity of the Neomycin-Sensing Riboswitch
"
Angewandte Chemie International Edition Engl 55 (4) (2016), 1527-1530
[DOI: 10.1002/anie.201507365]
[Abstract]
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A. Abdolzade-Bavil, A. von Kerczek, B.A. Cooksey, T. Kaufman T, P.A. Krasney, L. Pukac,
M. Görlach, A. Lammerich, C. Scheckermann, H. Allgaier, W.D. Shen, P. Liu
"Differential sensitivity of lipegfilgrastim and pegfilgrastim to neutrophil elastase
correlates with differences in clinical pharmacokinetic profile"
Journal of Clinical Pharmoacology 56 (2) (2016), 186-194
[DOI: 10.1002/jcph.578]
[Abstract]
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- 2015
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K. Reichwald, A. Petzold, P. Koch, B. R. Downie, N. Hartmann, S. Pietsch,
M. Baumgart, D. Chalopin, M. Felder, M. Bens, A. Sahm, K. Szafranski,
S. Taudien, M. Groth, I. Arisi, A. Weise, S. S. Bhatt, V. Sharma,
J. M. Kraus, F. Schmid, S. Priebe, T. Liehr, M. Görlach,
M. E. Than, M. Hiller, H. A. Kestler, J-N. Volff, M. Schartl,
A. Cellerino, Ch. Englert, M. Platzer
"Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish"
Cell 163 (6) 2015, 1527-38, online 3 Dec 2015
[DOI: 10.1016/j.cell.2015.10.071]
[Abstract]
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H. H. Brewitz, T. Kühl, N. Goradia, K. Galler, J. Popp, U. Neugebauer,
O. Ohlenschläger, D. Imhof
"Role of the chemical environment beyond the coordination site:
Structural insight into Fe(III) protoporphyrin binding to
cysteine-based heme-regulatory protein motifs"
ChemBioChem 16 (15) (2015), 2216, online 7 Sep 2015
[DOI: 10.1002/cbic.201500331]
[Abstract]
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C. Wiedemann, N. Goradia, S. Häfner, C. Herbst, M. Görlach,
O. Ohlenschläger, R. Ramachandran
"HN-NCA heteronuclear TOCSY-NH experiment for 1HN and 15N sequential
correlations in (13C, 15N) labelled intrinsically disordered proteins"
Journal of Biomolecular NMR 16 (2) (2015), 201-12, online 18 Aug 2015
[DOI: 10.1007/s10858-015-9976-x]
[Abstract]
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M. Hartlieb, D. Pretzel, M. Wagner, S. Hoeppner, P. Bellstedt,
M. Görlach, C. Englert, K. Kempe, U.S. Schubert
"Core cross-linked nanogels based on the self-assembly of double
hydrophilic poly(2-oxazoline) block copolymers"
Journal of Materials Chemistry B 9 (2015), 1748-1759, online 13 Jan 2015
[DOI: 10.1039/C4TB02069C]
[Abstract]
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C. Herbst, P. Bellstedt, M. Görlach, R. Ramachandran
"MAS solid state NMR of proteins: simultaneous 15N-13CA and 15N-13CO
dipolar recoupling via low-power symmetry-based RF pulse schemes"
Journal of Biomolecular NMR 62 (1) (2015), 7-15, online 25 Feb 2015
[DOI: 10.1007/s10858-015-9910-2]
[Abstract]
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C. Wiedemann, A. Szambowska, S. Häfner, O. Ohlenschläger,
K.-H. Gührs, M. Görlach
"Structure and regulatory role of the C-terminal winged helix domain
of the archaeal minichromosome maintenance complex"
Nucleic Acids Research 43 (5) (2015), 2958-2967, online 20 Feb 2015
[DOI: 10.1093/nar/gkv120]
[Open Access]
[Full Text (PDF)]
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N. Goradia, C. Wiedemann, C. Herbst, M. Görlach, S.H. Heinemann, O. Ohlenschläger, R. Ramachandran
"An approach to NMR assignment of intrinsically disordered proteins"
ChemPhysChem 16 (4) (2015), 739-746, online 11 Mar 2015
[DOI: 10.1002/cphc.201402872]
[Abstract]
- 2014
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C. Wiedemann, O. Ohlenschläger, B. Medagli, S. Onesti, M. Görlach
"1H, 15N and 13C chemical shift assignments for the winged helix
domains of two archeal MCM C-termini"
Biomolecular NMR Assignments 8 (2) 2014, 357-360
[DOI: 10.1007/s12104-013-9516-0]
[Abstract]
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S. T. Kumar, J. Meinhardt, A. K. Fuchs, T. Aumüller, J. Leppert, B. Büchele,
U. Knüpfer, R. Ramachandran, J. K. Yadav, E. Prell, I. Morgado, O. Ohlenschläger,
U. Horn, T. Simmet, M. Görlach, M. Fändrich
"Structure and Biomedical Applications of Amyloid Oligomer Nanoparticles"
ACS Nano 8 (11) (2014), 11042-11052
[DOI: 10.1021/nn503960h]
[Abstract]
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H. Keller, K. Kiosze, J. Sachsenweger, S. Haumann, O. Ohlenschläger,
T. Nuutinen, J. E. Syväoja, M. Görlach, F. Grosse, H. Pospiech
"The intrinsically disordered amino-terminal region of human RecQL4:
multiple DNA-binding domains confer annealing, strand exchange and G4
DNA binding"
Nucleic Acids Research 42 (20) (2014), 12614-12627
[DOI: 10.1093/nar/gku993]
[Open Access]
[Full Text (PDF)]
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C. Wiedemann, P. Bellstedt, M. Görlach
"PREdator: a python based GUI for data analysis, evaluation and fitting"
Source Code for Biology and Medicine 9 (21) (2014)
[DOI: 10.1186/1751-0473-9-21]
[Open Access]
[Full Text (PDF)]
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C. Wiedemann, P. Bellstedt, C. Herbst, M. Görlach, R. Ramachandran
"An approach to sequential NMR assignments of proteins:
application to chemical shift restraint-based structure prediction"
Journal of Biomolecular NMR 59 (4) (2014), 211-217
[DOI: 10.1007/s10858-014-9842-2]
[Abstract]
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P. Bellstedt, Y. Ihle, C. Wiedemann, A. Kirschstein, C. Herbst, M. Görlach, R. Ramachandran
"Sequential acquisition of multi-dimensional heteronuclear chemical shift correlation spectra with 1H detection"
Scientific Reports 4 (2014), Article number: 4490
[DOI: 10.1038/srep04490]
[Full Text]
[Full Text (PDF)]
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O. Ohlenschläger, A. Schiller, F. Jahns, S.H. Heinemann
"Bunte Aspekte: Häm und seine Abbauprodukte"
Nachrichten aus der Chemie 62 (2014), 119-124
[DOI: 10.1002/nadc.201490042]
[Abstract]
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M. Schmitt, A. Publicover, K. H. Orchard, M. Görlach, L. Wang, A. Schmitt,
J. Mani, P. Tsirigotis, R. Kuriakose, A. Nagler
"Biosimilar G-CSF Based Mobilization of Peripheral Blood Hematopoietic Stem Cells for
Autologous and Allogeneic Stem Cell Transplantation"
Theranostics 4 (3) (2014), 280-289
[DOI: 10.7150/thno.7752]
[Abstract]
[Full Text]
[Full Text (PDF)]
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C. Wiedemann, P. Bellstedt, A. Kirschstein, S. Häfner, C. Herbst, M. Görlach, R. Ramachandran
"Sequential protein NMR assignments in the liquid state via sequential data acquisition"
Journal of Magnetic Resonance 239 (2014), 23-28
[DOI: 10.1016/j.jmr.2013.12.002]
[Abstract]
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F. Bellmann, J. Leppert, M. Görlach, M. Krbetschek, D. Damidot, H.-M. Ludwig
"Analysis of disorder in tricalcium silicate by 29Si NMR spectroscopy and additional methods"
Cement and Concrete Research 57 (2014), 105-16.
[DOI: 10.1016/j.cemconres.2013.12.006]
[Abstract]
- 2013
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N. Sahoo, N. Goradia, O. Ohlenschläger, R. Schönherr, M. Friedrich, W. Plass,
R. Kappl, T. Hoshi, S.H. Heinemann
"Heme impairs the ball-and-chain inactivation of potassium channels"
Proceedings of the National Academy of Sciences of the USA 110 (42) (2013), E4036-E4044.
[DOI: 10.1073/pnas.1313247110]
[Abstract]
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P. Bellstedt, T. Seiboth, S. Häfner, H. Kutscha, R. Ramachandran, M. Görlach
"Resonance assignment for a particularly challenging protein based
on systematic unlabeling of amino acids to complement incomplete NMR data sets"
Journal of Biomolecular NMR 57 (2013), 65-72.
[DOI: 10.1007/s10858-013-9768-0]
>Abstract]
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T. Kühl, A. Wißbrock, N. Goradia, N. Sahoo, K. Galler, U. Neugebauer, J. Popp,
S. H. Heinemann, O. Ohlenschläger, D. Imhof
"Analysis of Fe(III) Heme Binding to Cysteine-Containing
Heme-Regulatory Motifs in Proteins"
ACS Chem Biol. 8 (8) (2013), 1785-1793.
[DOI: 10.1021/cb400317x]
[Abstract]
[Full Text]
[Full Text (PDF)]
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C. Wiedemann, P. Bellstedt, M. Görlach
"CAPITO--a web server-based analysis and plotting tool
for circular dichroism data"
Bioinformatics 29 (14) (2013), 1750-1757.
[DOI: 10.1093/bioinformatics/btt278]
[Abstract]
[Full Text]
[Full Text (PDF)]
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A. Mischo, O. Ohlenschläger, P. Hortschansky, R. Ramachandran, M. Görlach
"Structural Insights into a Wildtype Domain of the
Oncoprotein E6 and Its Interaction with a PDZ Domain"
PLoS ONE 8 (4) e62584 (2013), 1-13.
[DOI: 10.1371/journal.pone.0062584]
[Full Text]
[Full Text (PDF)]
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A. Mischo, O. Ohlenschläger, R. Ramachandran, M. Görlach,
"NMR assignment of a PDZ domain in complex with a HPV51 E6 derived N-terminally
pyroglutamic acid modified peptide"
Biomolecular NMR Assignments 7 (1) (2013), 47-49.
Epub 2012 Mar 6;
[DOI: 10.1007/s12104-012-9374-1]
[Abstract]
- 2012
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P. Bellstedt, C. Herbst, S. Häfner, J. Leppert, M. Görlach, R. Ramachandran
"Solid state NMR of proteins at high MAS frequencies: symmetry-based mixing
and simultaneous acquisition of chemical shift correlation spectra"
Journal of Biomolecular NMR 54 (2012), 325-335.
[DOI: 10.1007/s10858-012-9680-z]
[Abstract]
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I. Morgado, K. Wieligmann, M. Bereza, R. Rönicke, K. Meinhardt, K. Annamalai,
M. Baumann, J. Wacker, P. Hortschansky, M. Maleševic, C. Parthier, C. Mawrin,
C. Schiene-Fischer, K. G. Reymann, M. T. Stubbs, J. Balbach, M. Görlach,
U. Horn, M. Fändrich
"Molecular basis of β-amyloid oligomer recognition with a conformational antibody fragment"
Proceedings of the National Academy of Sciences of the USA 109 (2012), 12503-12508.
[DOI: 10.1073/pnas.1206433109]
[Abstract]
[Full Text (PDF)]
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O. Ohlenschläger, A. Kunert, A. Schneider, S. Haumann, P. Bellstedt, H. Keller,
H.-P. Saluz, P. Hortschansky, F. Hänel, F. Grosse, M. Görlach, H. Pospiech
"The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif"
Nucleic Acids Research 40 (2012), 8309-8324;
[DOI: 10.1093/nar/gks591]
[Abstract]
[Full Text]
[Full Text (PDF)]
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A. Mischo, O. Ohlenschläger, K.-H. Gührs, M. Görlach
"Recombinant production of isotope labeled peptides and spontaneous cyclization
of amino-terminal glutamine into pyroglutamic acid"
ChemBioChem 13 (2012), 1421-1423.
Epub 2012 May 22;
[DOI: 10.1002/cbic.201200178]
[Abstract]
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A. A. Tietze, D. Tietze, O. Ohlenschläger, E. Leipold, F. Ulrich, T. Kühl,
A. Mischo, G. Buntkowsky, M. Görlach, S. H. Heinemann, D. Imhof
"Structurally Diverse μ-Conotoxin PIIIA Isomers Block Sodium Channel NaV1.4* "
Angewandte Chemie International Edition Engl 51 (17) (2012), 4058-4061.
[DOI: 10.1002/anie.201107011]
[Abstract]
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C. Haupt, J. Leppert, R. Rönnike, J. Meinhardt, J.K. Yadav, R. Ramachandran,
O. Ohlenschläger, K.G. Reymann, M. Görlach, M. Fändrich
"Structural Basis of β-Amyloid-Dependent Synaptic Dysfunctions"
Angewandte Chemie International Edition Engl 51 (7) (2012), 1576-1579.
Epub 2012 Jan 10;
[DOI: 10.1002/anie.201105638]
[Abstract]
- 2011
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C. Herbst, J. Herbst, J. Leppert, O. Ohlenschläger, M. Görlach, R. Ramachandran
"Chemical shift correlation at high MAS frequencies employing
low-power symmetry-based mixing schemes"
Journal of Biomolecular NMR 50 (2011), 277-284.
[Abstract]
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M. Carella, J. Becher, O. Ohlenschläger, R. Ramachandran,
K.-H. Gührs, G. Wellenreuther, W. Meyer-Klaucke, S. H. Heinemann, M. Görlach
"Structure-function relationship in an archaebacterial methionine sulfoxide reductase B"
Molecular Microbiology 79 (2) (2011), 342-358.
[Abstract]
[PDB code:
2K8D]
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D. Tietze, S. Voigt, D. Mollenhauer, M. Tischler, D. Imhof, T. Gutmann, L. González,
O. Ohlenschläger, H. Breitzke, M. Görlach, G. Buntkowsky
"Revealing the position of the substrate in NiSOD: a model study"
Angewandte Chemie International Edition Engl 50 (13) (2011), 2946-2950.
[Abstract]
- 2010
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E. Duchardt-Ferner, J.E. Weigand, O. Ohlenschläger, S. R. Schmidtke, B. Suess, J. Wöhnert
"Highly Modular Structure and Ligand Binding by Conformational Capture in a Minimalistic Riboswitch"
Angewandte Chemie International Edition Engl 49 (2010), 6216-6219.
[DOI: 10.1002/anie.201001339]
[Abstract]
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D. Tietze, M. Tischler, S. Voigt, D. Imhof, O. Ohlenschläger, M. Görlach, G. Buntkowsky
"Development of a Functional cis-Prolyl Bond Biomimetic and Mechanistic Implications
for Nickel Superoxide Dismutase"
Chemistry 16 (25) (2010), 7572-7578.
[Abstract]
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A. Miloslavina, C. Ebert, D. Tietze, O. Ohlenschläger, C. Englert, M. Görlach, D. Imhof
"An unusual peptide from Conus villepinii: Synthesis, solution structure, and cardioactivity"
Peptides 31 (7) (2010), 1292-300.
[Abstract]
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M. Carella, O. Ohlenschläger, R. Ramachandran, M. Görlach
"1H, 13C and 15N resonance assignment of a zinc-binding methionine sulfoxide reductase
type-B from the thermophilic archeabacterium Methanothermobacter thermoautotrophicus"
Biomolecular NMR Assignments 4 (1) (2010), 93-95.
[Abstract]
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C. Herbst, J. Herbst, M. Carella, J. Leppert, O. Ohlenschläger, M. Görlach, R. Ramachandran
"Broadband 15N-13C dipolar recoupling via symmetry-based RF pulse schemes at high MAS frequencies"
Journal of Biomolecular NMR 47 (1) (2010), 7-17.
[Abstract]
- 2009
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N. Baum, C. Schiene-Fischer, M. Frost, M. Schumann, K. Sabapathy, O. Ohlenschläger, F. Grosse, B. Schlott
"The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies
its functions in cell cycle regulation and apoptosis"
Oncogene 28 (44) (2009), 3915-3925.
[Abstract]
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C. Herbst, J. Herbst, J. Leppert,
O. Ohlenschläger, M. Görlach, R. Ramachandran
"Numerical design of RNnν
symmetry-based RF pulse schemes for recoupling and
decoupling of nuclear spin interactions at high
MAS frequencies"
Journal of Biomolecular NMR 44 (4) (2009), 235-244.
[Abstract]
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C. Herbst, J. Herbst, A. Kirschstein, J. Leppert,
O. Ohlenschläger, M. Görlach, R. Ramachandran
"Recoupling and decoupling of nuclear spin interactions at high MAS frequencies:
Numerical design of CNnν symmetry-based RF pulse schemes"
Journal of Biomolecular NMR 44 (4) (2009), 175-184.
[Abstract]
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C. Herbst, J. Herbst, A. Kirschstein, J. Leppert,
O. Ohlenschläger, M. Görlach, R. Ramachandran
"Design of high-power,broadband 180° pulses and mixing
sequences for fast MAS solid state chemical shift
correlation NMR spectroscopy"
Journal of Biomolecular NMR 43 (1) (2009), 51-61.
[Abstract]
- 2008
-
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R. Zell, Y. Ihle, M. Effenberger, S. Seitz, P. Wutzler, M. Görlach
"Interaction of poly(rC)-binding protein 2 domains KH1 and KH3 with coxsackievirus RNA"
Biochemical and Biophysical Research Communications 377 (2) (2008), 500-3.
[Abstract]
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O. Ohlenschläger, S. Haumann, R. Ramachandran, M. Görlach
"Conformational signatures of 13C chemical shifts in RNA ribose"
Journal of Biomolecular NMR 42 (2) (2008), 139-42.
[Abstract]
-
C. Herbst, K. Riedel, Y. Ihle, J. Leppert,
O. Ohlenschläger, M. Görlach, R. Ramachandran
"MAS solid state NMR of RNAs with multiple receivers"
Journal of Biomolecular NMR 41 (3) (2008), 121-5
[Abstract]
-
M. Schmidt, S. Zahn, M. Carella, O. Ohlenschläger,
M. Görlach, E. Kothe, J. Weston
"Solution Structure of a Functional Biomimeticum and Mechanistic
Implications for Nickel Superoxide Dismutases"
ChemBioChem 9 (13) (2008), 2135-46
[Abstract]
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A. Kirschstein, C. Herbst, K. Riedel, M. Carella, J. Leppert,
O. Ohlenschläger, M. Görlach, R. Ramachandran
"Heteronuclear J cross-polarisation in liquids using
amplitude and phase modulated mixing sequences"
Journal of Biomolecular NMR 40 (4) (2008), 277-83
[Abstract]
-
A. Kirschstein, C. Herbst, K. Riedel, M. Carella, J. Leppert,
O. Ohlenschläger, M. Görlach, R. Ramachandran
"Broadband homonuclear TOCSY with amplitude and phase-modulated
RF mixing schemes"
Journal of Biomolecular NMR 40 (4) (2008), 227-37
[Abstract]
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D.T. Huong, N.T.H. Van, C. Kamperdick, N.T.H. Anh, T.V. Sung
"Two new bis-styryl compounds from Miliusa balansae"
Zeitschrift für Naturforschung 63b (2008), 335-8
[Abstract]
-
M. Schwalbe, O. Ohlenschäger, A. Marchanka, R. Ramachandran,
S. Häfner, T. Heise and M. Görlach
"Solution structure of stem-loop α of the hepatitis B virus
post-transcriptional regulatory element"
Nucleic Acids Research 36 (5) (2008), 1681-9
[Abstract]
- 2007
-
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R. Zell, Y. Ihle, S. Seitz, U. Gündel, P. Wutzler, and M. Görlach
"Poly(rC)-binding protein 2 interacts with the oligo(rC) tract of coxsackievirus B3"
Biochem Biophys Res Commun. 366 (4) (2008 Feb 22), 917-21.
[Abstract]
-
C. Herbst, K. Riedel, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"13C - 13C
chemical shift correlation in rotating solids without
1H decoupling during mixing: An
assessment of amplitude and phase modulated adiabatic RF pulse schemes"
Chemphyschem 8 (2007), 1770-1773.
[Abstract]
-
K. Riedel, C. Herbst, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Broadband homonuclear chemical shift correlation at high MAS frequencies: A study of tanh/tan
adiabatic RF pulse schemes without 1H decoupling during mixing"
Journal of Biomolecular NMR 37 (4) (2007), 277-286.
[Abstract]
- 2006
-
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K. Riedel, C. Herbst, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Heteronuclear decoupling in rotating solids: Improving the efficacy of CN n
ν symmetry-based tanh/tan adiabatic RF pulse schemes"
Chemical Physics Letters 429 (4-6) (2006), 590-594
[Abstract]
-
K. Riedel, C. Herbst, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Tailoring broadband inversion pulses for MAS solid state NMR"
Journal of Biomolecular NMR 35 (2006), 275-283.
[Abstract]
-
C. Herbst, K. Riedel, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Solid state NMR at high magic angle spinning frequencies: Dipolar chemical shift correlation with
adiabatic inversion pulse based RF pulse schemes"
Journal of Biomolecular NMR 35 (2006), 241-248.
[Abstract]
-
K. Riedel, C. Herbst, S. Häfner, J. Leppert, O. Ohlenschläger, M.S. Swanson, M. Görlach and R. Ramachandran
"Constraints on the Structure of (CUG)97-RNA from MAS solid State NMR Spectroscopy"
Angewandte Chemie 45 (2006), 5620-5623.
[Abstract]
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K. Riedel, C. Herbst, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Broadband homonuclear double-quantum NMR/filtering via zero-quantum dipolar recoupling in rotating solids"
Chemical Physics Letters 424 (2006), 178-183.
[Abstract]
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O. Ohlenschläger, T. Seiboth, H. Zengerling, L. Briese, A. Marchanka, R. Ramachandran,
M. Baum, M. Korbas, W. Meyer-Klaucke, M. Dürst, M. Görlach
"Solution structure of the partially folded high-risk HPV 45 oncoprotein E7"
Oncogene 25 (2006), 5953-5959;
DOI: 10.1038/sj.onc.1209584.
[Abstract]
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D. Hölscher, M. Reichert, H. Görls, O. Ohlenschläger, G. Bringmann, B. Schneider
"Monolaterol, the first configurationally assigned phenylphenalenone derivative with a stereogenic
center at C-9, from Monochoria elata"
Journal of Natural Products 69 (11) 2006, 1614-7.
[Abstract]
- D. Musumeci, M. Valente, D. Capasso, R. Palumbo, M. Görlach,
M. Schmidtke, R. Zell, G.N. Roviello, R. Sapio, C. Pedone, E.M. Bucci
"A short PNA targeting coxsackievirus B3 5'-nontranslated region prevents virus-induced cytolysis"
J. Pept. Sci. 12 (3) (2006), 161-70.
[Abstract]
- 2005
-
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A. Randazzo, V. Esposito, O. Ohlenschläger, R. Ramachandran, A. Virgilio, L. Mayol
"Structural Studies on LNA Quadruplexes"
Nucleosides Nucleotides Nucleic Acids 24 (5-7) (2005), 795-800.
[Abstract]
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S. Ilin, A. Hoskins, O. Ohlenschläger, H.R.A. Jonker, H. Schwalbe and J. Wöhnert
"Domain Reorientation and Induced Fit upon RNA Binding: Solution Structure and Dynamics of
Ribosomal Protein L11 from Thermotoga maritima"
ChemBioChem 6 (9) (2005), 1611-1618.
[Abstract]
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Y. Ihle, O. Ohlenschläger, S. Häfner, E. Duchardt, M. Zacharias, S. Seitz,
R. Zell, R. Ramachandran and M. Görlach
"A novel cGUUAg tetraloop structure with a conserved yYNMGg type backbone conformation
from cloverleaf 1 of bovine enterovirus 1 RNA"
Nucleic Acids Research 33 (6) (2005), 2003-2011.
[Full Text]
-
K. Riedel, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Characterisation of hydrogen bonding networks in RNAs via magic angle spinning solid
state NMR spectroscopy"
Journal of Biomolecular NMR 31 (2005), 331-336.
[Abstract]
-
K. Riedel, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"TEDOR with adiabatic inversion pulses: Resonance assignments of 13C/15N labelled RNAs"
Journal of Biomolecular NMR
31 (1) (2005), 49-57.
[Abstract]
- 2004
-
-
K. Riedel, J. Leppert, S. Häfner, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Homonuclear chemical shift correlation in rotating solids via RNn
ν symmetry-based adiabatic RF pulse schemes"
Journal of Biomolecular NMR
30 (4) (2004), 389-95.
[Abstract]
-
M. Carella, R. Ramachandran, B. Schlott, J. Leppert, E. Glusa and O. Ohlenschläger
"1H, 13C and
15N NMR sequence-specific resonance assignments
of the two-domain thrombin inhibitor dipetalin"
Journal of Biomolecular NMR
30 (3) (2004), 383-4.
-
K. Riedel, J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Heteronuclear decoupling in rotating solids via symmetry-based adiabatic RF pulse schemes"
Chemical Physics Letters 395
(2004), 356-361.
[Abstract]
-
A. Randazzo, V. Esposito, O. Ohlenschläger, R. Ramachandran and L. Mayol
"NMR solution structure of a parallel LNA quadruplex"
Nucleic Acids Research 32
(2004), 3083-3092.
[Full Text]
-
M. Leone, P. Di Lello, O. Ohlenschläger, E.M. Pedone, S. Bartolucci, M. Rossi, B. Di Blasio,
C. Pedone, M. Saviano, C. Isernia, R. Fattorusso
"Solution Structure and Backbone Dynamics of the K18G/R82E Alicyclobacillus acidocaldarius
Thioredoxin Mutant: A Molecular Analysis of Its Reduced Thermal Stability"
Biochemistry 43 (2004), 6043-6058.
[Abstract]
-
J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Adiabatic heteronuclear decoupling in rotating solids"
Journal of Biomolecular NMR 29 (3) (2004), 319-324.
[ Abstract]
-
J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Adiabatic TOBSY in rotating solids"
Journal of Biomolecular NMR 29 (2) (2004), 167-173.
[Abstract]
-
E. Duchardt, C. Richter, O. Ohlenschläger, M. Görlach, J. Wöhnert, H. Schwalbe
"Determination of the Glycosidic Bond Angle χ in RNA from Cross-Correlated Relaxation
of CH Dipolar Coupling and N Chemical Shift Anisotropy"
Journal of the American Chemical Society 12 (2004), 1962-1970.
[Abstract]
-
J. Leppert, C. Urbinati, S. Häfner, O. Ohlenschläger, M.S. Swanson, M. Görlach and R. Ramachandran
"Identification of NH...N hydrogen bonds by magic angle spinning solid state NMR in a double-stranded
RNA associated with myotonic dystrophy"
Nucleic Acids Research 32 (2004), 1177-1183.
[Full Text]
-
O. Ohlenschläger, J. Wöhnert, E. Bucci, S. Seitz, S. Häfner, R. Ramachandran, R. Zell, M. Görlach
"The Structure of the Stemloop D Subdomain of Coxsackievirus B3 Cloverleaf RNA and its Interaction with the Proteinase 3C"
Structure 12 (2004), 237-248.
[Abstract]
[PDB code:
1RFR]
-
J. Leppert, O. Ohlenschläger, M. Görlach and R. Ramachandran
"RFDR with adiabatic inversion pulses: Application to internuclear distance measurements"
Journal of Biomolecular NMR 28 (3) (2004), 229-233.
[ Abstract ]
-
J. Leppert, B. Heise, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Triple resonance MAS NMR with (13C,15N)
labelled molecules: reduced dimensionality data acquisition via 13C-
15N heteronuclear two-spin coherence transfer pathways"
Journal of Biomolecular NMR 28 (2) (2004), 185-190.
[Abstract]
-
S. Zhang, B. Schlott, M. Görlach, F. Grosse
"DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in
an RNA-dependent manner"
Nucleic Acids Research 32 (2004), 1-10.
[Full Text]
-
M. Stoldt, E. Kupce , B. H. A. Rehm and M. Görlach
"Backbone resonance assignment of an aminoglycoside-3'-phosphotransferase type IIa"
Journal of Biomolecular NMR 28 (2004), 93-94.
[Abstract]
- 2003
-
-
R. Zell, R. Markgraf, M. Schmidtke, M. Görlach, A. Stelzner, A. Henke, H.H. Sigusch, B. Gluck
"Nitric oxide donors inhibit the coxsackievirus B3 proteinases 2A and 3C in vitro, virus production in cells,
and signs of myocarditis in virus-infected mice"
Medical Microbiology and Immunology 193 (2-3) (2003), 91-100
[Abstract]
-
D. Krumme, H. Budde, H.-J. Hecht, U. Menge, O. Ohlenschläger, A. Ross, J. Wissing, V. Wray, and L. Flohe
"NMR Studies of the Interaction of Tryparedoxin with Redox-Inactive Substrate Homologues"
Biochemistry 42 (2003), 14720-14728.
[Abstract]
-
O. Ohlenschläger, J. Wöhnert, R. Ramachandran, C. Sich and M. Görlach
"Nuclear magnetic resonance studies of ribonucleic acids"
Spectroscopy 17 (2003), 537-547.
[Abstract]
-
J. Drenth, K. Dijkstra and C. Haas, J. Leppert and O. Ohlenschläger
"Effect of molecular anisotropy on the nucleation of lysozyme"
Journal of Physical Chemistry B 107 (2003), 4203-4207.
[Abstract]
-
J. Leppert, B. Heise, O. Ohlenschläger, M. Görlach and R. Ramachandran
"Broadband RFDR with adiabatic inversion pulses"
Journal of Biomolecular NMR 26 (2003), 13-24.
[Abstract]
-
J. Wöhnert, M. Görlach and H. Schwalbe
"Triple resonance experiments for the simultaneous correlation of H6/H5 and exchangeable protons of pyrimidine nucleotides
in 13C,15N-labeled RNA applicable to larger RNA molecules"
Journal of Biomolecular NMR 26 (2003), 79-83.
[Abstract]
-
M. Sharon, N. Kessler, R. Levy, S. Zolla-Pazner, M. Görlach and J. Anglister
"Alternative conformations of HIV-1 V3 loops mimic β hairpins in chemokines, suggesting
a mechanism for coreceptor selectivity"
Structure 11 (2) (2003), 225-236.
[Abstract]
[Commentary paper]
-
M. Palczewska, P. Groves, G. Batta, B. Heise and J. Kuznicki
"Calretinin and calbindin D28k have different domain organizations"
Protein Science 12 (2003), 180-184.
[Full Text]
[Full Text (PDF)]
- 2002
-
- B. Heise, J. Leppert, O.
Ohlenschläger, M. Görlach and R. Ramachandran
"Chemical shift correlation via RFDR: Elimination of resonance offset effects"
Journal of Biomolecular NMR 24
(2002), 237-243. [
Abstract]
- J. Leppert, B. Heise, M. Görlach and R. Ramachandran
"REDOR: An assessment of the efficacy of dipolar recoupling with adiabatic inversion
pulses"
Journal of Biomolecular NMR 23
(2002), 227-238. [
Abstract]
- C. Icke, B. Schlott, O. Ohlenschläger, M. Hartmann, K. Gührs and E. Glusa
"Fusion proteins with anticoagulant and fibrinolytic properties: functional studies and
structural considerations"
Molecular Pharmacology 62 (2002), 203-209.
[
Abstract]
[
PDF file]
- O. Ohlenschläger, H. Hojo, R. Ramachandran, M. Görlach and P. I. Haris
"Three-dimensional Structure of the S4-S5 Segment of the Shaker Potassium Channel"
Biophysical Journal 82 (2002),
2995-3002.
[ Abstract]
[PDB codes:
1HO2,
1HO7]
-
B. Schlott, J. Wöhnert, C. Icke, M. Hartmann, R. Ramachandran, K. Gührs,
E. Glusa, J. Flemming, M. Görlach, F
Große and O. Ohlenschläger.
"Interaction of Kazal-type inhibitor domains with serine proteinases: Biochemical and
structural studies"
Journal of Molecular Biology 318
(2002), 533-546. [
Abstract] [PDB code:
1KMA]
- M. Sharon, M. Görlach, R. Levy, Y. Hayek and J. Anglister
"Expression purification and isotope labeling of a gp120 V3 peptide and production of a Fab
from a human HIV-1 neutralizing antibody for NMR studies"
Protein Expression and Purification
24/3 (2002), 374-383. [
Abstract]
- S. Zhang, K. Buder, C. Burkhardt, B. Schlott, M. Görlach and F. Große
"Nuclear DNA helicase II/RNA helicase A binds to filamentous actin (F-actin)"
Journal of Biological Chemistry
277/1 (2002), 843-853. [
Abstract]
- R. Zell, K. Sidigi, E. Bucci, A. Stelzner and M. Görlach
"Determinants of the recognition of enteroviral cloverleaf RNA by coxsackievirus B3 proteinase 3C"
RNA 8 (2002), 188-201.
[
Abstract]
- 2001
-
-
J. Leppert, B. Heise and R. Ramachandran
"Orientational information from TEDOR spectral sidebands"
Solid State Nuclear Magnetic Resonance 19 (2001), 1-18.
[Abstract]
-
B. Heise, J. Leppert, H. Wenschuh, O. Ohlenschläger, M. Görlach and R. Ramachandran
"2D relayed anisotropy correlation NMR: characterization of the 13C'
chemical shift tensor orientation in the peptide plane of the dipeptide Aib-Aib"
Journal of Biomolecular NMR 19 (2001), 167-179.
[Abstract]
- 2000
-
-
J. Leppert, B. Heise and R. Ramachandran
"REDOR in IS1S2 systems"
Journal of Biomolecular NMR 18 (2000), 153-164.
[Abstract]
-
B. Heise, J. Leppert and R. Ramachandran
"REDOR with adiabatic dephasing pulses"
Journal of Magnetic Resonance 146 (2000), 181-187. [Abstract]
- J. Leppert, B. Heise and R. Ramachandran
"15N
chemical shift tensor magnitude and orientation
in the molecular frame of uracil determined via
MAS NMR"
Journal of Magnetic Resonance
145 (2000), 307-314. [
Abstract]
- F. Mueller, I. Sommer, P. Baranov, R. Matadeen, M. Stoldt, J. Wöhnert,
M. Görlach, M. van Heel and R. Brimacombe
"The 3D arrangement of the 23S and 5S rRNA in the Escherichia coli 50S ribosomal
subunit at 7.5 Å resolution"
Journal of Molecular Biology 298
(2000), 35-59. [
Abstract] [PDB codes:
1C2W,
1C2X]
- B. Heise, J. Leppert and R. Ramachandran
"Characterization of 15N chemical shift tensors
via 15N-13
C REDOR and 15N-
1H dipolar-shift CPMAS NMR
spectroscopy"
Solid State Nuclear Magnetic Resonance
16/3 (2000), 177-187. [
Abstract]
-
R. Anders, O. Ohlenschläger, V. Soskic, H. Wenschuh, B. Heise and L. R. Brown
"The NMR solution structure of the ion channel peptaibol chrysospermin C bound to dodecylphosphocholine micelles"
European Journal of Biochemistry 267/6 (2000), 1784-1794.
[Abstract]
[PDB code:
1EE7]
- 1999
-
-
M. Stoldt, J. Wöhnert, O. Ohlenschläger, M. Görlach and L. R. Brown
"The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition"
EMBO Journal 18 (1999), 6508-6521.
[Abstract]
[PDB code:
1D6K]
-
J. Wöhnert, A. J. Dingley, M. Stoldt, M. Görlach, S. Grzesiek and L. R. Brown
"Direct identification of NH···N hydrogen bonds in
noncanonical base pairs of RNA by NMR spectroscopy"
Nucleic Acids Research 15
(1999), 3104-3110.
[
Abstract]
-
J. Wöhnert, R. Ramachandran, M. Görlach and L. R. Brown
"Triple resonance experiments for correlation of H5 and exchangeable pyrimidine base
hydrogens in 13C, 15
N labelled RNA"
Journal of Magnetic Resonance
139 (1999), 430-433.
[Abstract]
-
J. Leppert, B. Heise and R. Ramachandran
"Magic angle spinning NMR spectroscopy with composite RF pulses"
Journal of Magnetic Resonance
139 (1999), 382-388.
[Abstract]
- V. Soskic, M. Görlach, S. Poznanovic, F. D. Boehmer and J. Godovac-Zimmermann
"Functional proteomics analysis of signal transduction pathways of the platelet-derived
growth factor ß receptor"
Biochemistry 38 (1999),
1757-1764. [
Abstract]
-
O. Ohlenschläger, R. Ramachandran, K. Gührs, B. Schlott and L. R. Brown
"Structural investigations on the activation of plasminogen by staphylokinase"
Bulletin of Magnetic Resonance 20 (1/4) (1999), 35-38.
[PDF file]
- 1998
-
- P. Güntert, M. Billeter, O. Ohlenschläger, L. R. Brown and K. Wüthrich
"Conformation analysis of protein and nucleic
acid fragments with the new grid search
algorithm FOUND"
Journal of Biomolecular NMR 12
(1998), 543-548. [
Abstract]
- M. Stoldt, J. Wöhnert, M. Görlach, and L. R. Brown
"The NMR structure of Escherichia coli ribosomal protein L25 shows homology to general
stress proteins and glutaminyl-tRNA synthetases"
EMBO Journal 17 (1998),
6377-6384. [
Abstract] [PDB code:
1B75]
- O. Ohlenschläger, R. Ramachandran, K. Gührs, B. Schlott and L. R. Brown
"Nuclear magnetic resonance solution structure of the plasminogen-activator protein
staphylokinase"
Biochemistry 37 (1998),
10635-10642. [
Abstract] [PDB code:
1SSN]
- R. Anders, H. Wenschuh, V. Soskic, S. Fischer-Frühholz, O. Ohlenschläger,
K. Dornberger and L. R. Brown
"A solution NMR study of the selectively 13C,
15N labelled peptaibol chrysospermin C in methanol"
Journal of Peptide Research 52
(1998), 34-44. [
Abstract]
- 1997
-
- H. Ottleben, M. Haasemann, R. Ramachandran, W. Müller-Esterl and L. R. Brown
"NMR investigations of recombinant 15N/13 C/2H-labeled Bradykinin bound
to a Fab mimic of the B2 receptor"
Receptors and Channels 3 (1997),
201-205. [
Abstract]
- C. Sich, O. Ohlenschläger, R. Ramachandran, M. Görlach and L. R. Brown
"Structure of an RNA hairpin loop with a 5'-CGUUUCG-3' loop motif by heteronuclear NMR
spectroscopy and distance geometry"
Biochemistry 36 (1997),
13989-14002. [
Abstract] [PDB code:
1UUU]
- O. Ohlenschläger, R. Ramachandran, J. Flemming, K. Gührs, B. Schlott and L. R. Brown
"NMR secondary structure of the plasminogen activator protein staphylokinase"
Journal of Biomolecular NMR 9
(1997), 273-286. [
Abstract]
- H. Ottleben, M. Haasemann, R. Ramachandran, M. Görlach, W. Müller-Esterl and L. R. Brown
"An NMR study of the interaction of 15N-labelled
bradykinin with an antibody mimic of the bradykinin B2 receptor"
European Journal of Biochemistry
244 (1997), 471-478. [
Abstract]
- R. Ramachandran, C. Sich, O. Ohlenschläger and L. R. Brown
"Identification of ribose-base sequential NOEs according to base types in uniformly
13C-labeled
RNAs",
Journal of Magnetic Resonance
124 (1997), 210-213. [
Abstract]
- 1996
-
- C. Sich, J. Flemming, R. Ramachandran and L. R. Brown
"Distinguishing inter- and intrastrand NOEs involving exchangeable protons in RNA duplexes"
Journal of Magnetic Resonance Series B
112 (1996), 275-281. [
Abstract]
- M. Grüne, J. P. Fürste, S. Klußmann, V. A. Erdmann and L. R. Brown
"Detection of multiple conformations of the E-domain of 5S rRNA from E. coli in
solution and in crystals by NMR spectroscopy"
Nucleic Acids Research 24
(1996), 2592-2596. [
Abstract]
- R. Ramachandran, C. Sich, M. Grüne, V. Soskic and L. R. Brown
"Sequential assignments in uniformly 13C and
15N labelled
RNAs: The HC(N,P) and HC(N,P)-CCH-TOCSY Experiments"
Journal of Biomolecular NMR 7
(1996), 251-255. [
Abstract]
- M. Grüne, M. Görlach, V. Soskic, S. Klußmann, R. Bald, J. P. Fürste,
V. A. Erdmann and L. R. Brown
"Initial analysis of 750 MHz NMR spectra of selectively [15N]-G,U labelled E.
coli 5S rRNA"
FEBS Letters 385 (1996),
114-118. [
Abstract]
-
N. Goradia
"Structure determination of peptide-heme complexes"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(to be published in 2016)
-
C. Wiedemann
"The C-terminal winged helix domain of the archael minichromosome
maintenance complex: structure and regulatory role"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(2015)
[ PDF file] (54 MiB)
-
P. Bellstedt
"Evidence for multiple functions of Aprataxin in DNA damage repair"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(2014)
[ PDF file] (15.84 MiB)
-
A. Mischo
"Structural insights into the interaction of a high-risk human papillomavirus wild-type oncoprotein E6"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(2012)
[ PDF file] (4.9 MiB)
-
C. Herbst
"Korrelationen der chemischen Verschiebung an schnell rotierenden biologischen
Festkörpern mittels NMR-Spektroskopie"
PhD thesis,
Physikalisch-Astronomische Fakultät Friedrich-Schiller-Universität Jena
(2010)
[ PDF file] (4.72 MiB)
-
J. Meinhardt
"Structural Polymorphism of Alzheimer's Amyloid-β Aggregates"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(2010)
[ PDF file] (14 MiB)
-
M. Carella
"Structural Characterisation of Type-B Methionine Sulfoxide Reductases"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(2008)
[ PDF file] (27 MiB)
-
K. Riedel
"Methoden zur Untersuchung biologischer Moleküle mittels
Festkörper-Kernresonanzspektroskopie"
PhD thesis,
Physikalisch-Astronomische Fakultät Friedrich-Schiller-Universität Jena
(2007)
[ PDF file] (3.5 MiB)
-
K. Sidigi
"RNA: Protein Interaktion von Enteroviraler Cloverleaf-RNA und Coxsackievirus B3 Proteinase 3 C"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(2002)
-
E. Bucci
"L'interazione fra la proteasi 3Cpro e l'RNA genomico virale nei picornavirus: aspetti biochimici
e strutturali in CVB3"
(Interaktion zwischen der 3C Protease und der viralen genomischen RNA in Picornaviren:
Biochemische und strukturelle Aspekte in CVB3)
PhD thesis,
Università degli Studi di Napoli "Federico II"
Italy (2002)
-
B. Heise
"NMR-Spektroskopie an Peptaibolen im Festkörper und in Lösung: Chemische
Verschiebungstensoren in α-Aminoisobuttersäure und Strukturuntersuchungen an
Chrysospermin C"
PhD thesis,
Physikalisch-Astronomische Fakultät Friedrich-Schiller-Universität Jena
(2001)
[ PDF file] (13 MB)
-
J. Leppert
"Charakterisierung des chemischen Verschiebungstensors mittels heteronuklearer
Festkörper-Kernresonanzspektroskopie"
PhD thesis,
Physikalisch-Astronomische Fakultät Friedrich-Schiller-Universität Jena
(2001)
-
J. Wöhnert
"Die Struktur der E-Domäne der 5S ribosomalen RNA aus Escherichia coli in
Lösung: Kernresonanzspektroskopische Untersuchungen der RNA in freier Form und
gebunden an das ribosomale Protein L25"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(2001)
-
M. Stoldt
"Kernmagnetresonanz-Raumstruktur des ribosomalen Proteins L25 aus Escherichia coli
in freier und in RNA-gebundener Form"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(2001)
-
H. Ottleben
"Konformationsbestimmung von rekombinantem Bradykinin gebunden an ein Fab-Fragment-Modell
des B2-Rezeptors mittels heteronuklearer NMR-Spektroskopie"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(1998)
-
C. Sich
"Kernresonanzspektroskopische Untersuchungen zur Struktur der 5'-UUU-3'-Sequenz in
RNA-Haarnadel- und Duplex-Konformation"
PhD thesis,
Biologisch-Pharmazeutische Fakultät Friedrich-Schiller-Universität Jena
(1997)
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Last update: Friday, 07-Jun-2019 14:56:27 CEST